Organ Doses and Radiation Risk of Computed Tomographic Coronary Angiography in a Clinical Patient Population: How Do Low-Dose Acquisition Modes Compare?

J Comput Assist Tomogr. 2015 Jul-Aug;39(4):591-7. doi: 10.1097/RCT.0000000000000253.

Abstract

Objective: To compare the organ doses and lifetime-attributable risk of cancer for electrocardiogram-triggered sequential and high-pitch helical scanning in a clinical patient population.

Methods: Phantom thermoluminiscence dosimeter measurements were used as a model for the organ dose assessment of 314 individual patients who underwent coronary computed tomographic angiography. Patient-specific lifetime-attributable cancer risks were calculated.

Results: Phantom measurements showed that heart rate had a significant influence on the delivered radiation exposure in sequential mode, and calcium scoring and contrast bolus tracking scans make a nonnegligible contribution to patients' dose. Therefore, they should be taken into account for patients' organ dose estimations. Median cancer induction risks are low, with 0.008% (0.0016%) and 0.022% (0.056%) for high-pitch and sequential scanning for men (women), respectively.

Conclusions: The use of high-pitch helical scanning leads to 65% and 72% lower lifetime-attributable risk values for men and women, respectively, compared with sequential scanning.

Publication types

  • Comparative Study

MeSH terms

  • Cardiac-Gated Imaging Techniques
  • Cohort Studies
  • Coronary Angiography / methods*
  • Female
  • Heart
  • Heart Rate
  • Humans
  • Male
  • Phantoms, Imaging
  • Radiation Dosage*
  • Radiographic Image Interpretation, Computer-Assisted
  • Retrospective Studies
  • Risk
  • Thermoluminescent Dosimetry / statistics & numerical data
  • Tomography, Spiral Computed / methods*