First detection of insertion sequence element ISPa1328 in the oprD porin gene of an imipenem-resistant Pseudomonas aeruginosa isolate from an idiopathic pulmonary fibrosis patient in Marseille, France

C Al-Bayssari; C Valentini; C Gomez; M Reynaud-Gaubert; J-M Rolain

doi:10.1016/j.nmni.2015.05.004

First detection of insertion sequence element ISPa1328 in the oprD porin gene of an imipenem-resistant Pseudomonas aeruginosa isolate from an idiopathic pulmonary fibrosis patient in Marseille, France

New Microbes New Infect. 2015 May 14:7:26-7. doi: 10.1016/j.nmni.2015.05.004. eCollection 2015 Sep.

Authors

C Al-Bayssari¹, C Valentini¹, C Gomez², M Reynaud-Gaubert², J-M Rolain¹

Affiliations

¹ Aix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), UM63, CNRS 7278, IRD 198, Inserm 1095, IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, France.
² Service de Pneumologie, Centre de Soins de la Mucoviscidose (CRCM) et en Transplantation Pulmonaire Adulte, Hôpital Nord, Marseille, France.

Abstract

We report here the first case of a carbapenem-resistant Pseudomonas aeruginosa clinical isolate harboring the insertion sequence (IS) element ISPa1328 in the oprD gene in an idiopathic pulmonary fibrosis patient in France previously treated with imipenem.

Keywords: Carbapenem resistance; Pseudomonas aeruginosa; insertion sequence; oprD gene; pulmonary fibrosis.