Evolution of Influenza B Virus in Kuala Lumpur, Malaysia, between 1995 and 2008

J Virol. 2015 Sep;89(18):9689-92. doi: 10.1128/JVI.00708-15. Epub 2015 Jul 1.

Abstract

Influenza B virus causes significant disease but remains understudied in tropical regions. We sequenced 72 influenza B viruses collected in Kuala Lumpur, Malaysia, from 1995 to 2008. The predominant circulating lineage (Victoria or Yamagata) changed every 1 to 3 years, and these shifts were associated with increased incidence of influenza B. We also found poor lineage matches with recommended influenza virus vaccine strains. While most influenza B virus lineages in Malaysia were short-lived, one circulated for 3 to 4 years.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Evolution, Molecular*
  • Female
  • Humans
  • Influenza B virus / genetics*
  • Influenza, Human / epidemiology
  • Influenza, Human / genetics*
  • Malaysia / epidemiology
  • Male
  • Molecular Sequence Data

Associated data

  • GENBANK/CY118283
  • GENBANK/CY118417
  • GENBANK/CY119546
  • GENBANK/CY120017
  • GENBANK/CY120029
  • GENBANK/CY120046