Dynamic multidetector CT and non-contrast-enhanced MR for right adrenal vein imaging: comparison with catheter venography in adrenal venous sampling

Eur Radiol. 2016 Mar;26(3):622-30. doi: 10.1007/s00330-015-3872-3. Epub 2015 Jun 25.

Abstract

Objectives: To evaluate visualization of the right adrenal vein (RAV) with multidetector CT and non-contrast-enhanced MR imaging in patients with primary aldosteronism.

Methods: A total of 125 patients (67 men) scheduled for adrenal venous sampling (AVS) were included. Dynamic 64-detector-row CT and balanced steady-state free precession-based non-contrast-enhanced 3-T MR imaging were performed. RAV visualization based on a four-point score was documented. Both anatomical location and variation on cross-sectional imaging were evaluated, and the findings were compared with catheter venography as the gold standard.

Results: The RAV was visualized in 93.2% by CT and 84.8% by MR imaging (p = 0.02). Positive predictive values of RAV visualization were 100% for CT and 95.2% for MR imaging. Imaging score was significantly higher in CT than MR imaging (p < 0.01). The RAV formed a common trunk with an accessory hepatic vein in 16% of patients. The RAV orifice level on cross-sectional imaging was concordant with catheter venography within the range of 1/3 vertebral height in >70% of subjects. Success rate of AVS was 99.2%.

Conclusions: Dynamic CT is a reliable way to map the RAV prior to AVS. Non-contrast-enhanced MR imaging is an alternative when there is a risk of complication from contrast media or radiation exposure.

Key points: Dynamic CT and non-contrast-enhanced MR imaging detect the right adrenal vein (RAV). Dynamic CT can visualize the RAV more than non-contrast-enhanced MR imaging. Mapping the RAV helps to achieve successful adrenal venous sampling. Sixteen per cent of RAVs share the common trunk with accessory hepatic veins.

Keywords: Angiography, digital subtraction; Hyperaldosteronism; Magnetic resonance imaging; Multidetector computed tomography; Phlebography.

Publication types

  • Comparative Study

MeSH terms

  • Adrenal Glands / blood supply*
  • Adrenal Glands / diagnostic imaging
  • Adult
  • Aged
  • Anatomic Variation
  • Anatomy, Cross-Sectional / methods
  • Catheterization, Peripheral / methods
  • Contrast Media
  • Female
  • Hepatic Veins / diagnostic imaging
  • Humans
  • Hyperaldosteronism / diagnostic imaging*
  • Image Interpretation, Computer-Assisted / methods
  • Magnetic Resonance Angiography / methods*
  • Magnetic Resonance Angiography / statistics & numerical data
  • Male
  • Middle Aged
  • Multidetector Computed Tomography / methods*
  • Multidetector Computed Tomography / statistics & numerical data
  • Multimodal Imaging / methods*
  • Multimodal Imaging / statistics & numerical data
  • Phlebography / instrumentation
  • Phlebography / methods*
  • Predictive Value of Tests
  • Vena Cava, Inferior / diagnostic imaging

Substances

  • Contrast Media