CpG-DNA enhances the tight junction integrity of the bronchial epithelial cell barrier

J Allergy Clin Immunol. 2015 Nov;136(5):1413-6.e1-8. doi: 10.1016/j.jaci.2015.05.006. Epub 2015 Jun 19.

Affiliations

¹ Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; Christine Kühne-Center for Allergy Research and Education, Davos, Switzerland.
² Department of Internal Medicine, Jagiellonian University, Krakow, Poland.
³ Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; Christine Kühne-Center for Allergy Research and Education, Davos, Switzerland. Electronic address: akdisac@siaf.uzh.ch.

PMID: 26100085
DOI: 10.1016/j.jaci.2015.05.006

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Asthma / immunology*
Bronchi / cytology*
Cell Membrane Permeability / drug effects
Cells, Cultured
Claudin-4 / genetics
Claudin-4 / metabolism
Electric Impedance
Epithelial Cells / drug effects*
Epithelial Cells / physiology
Humans
Hygiene Hypothesis
Interleukin-13 / metabolism
Oligodeoxyribonucleotides / pharmacology*
Tight Junctions / drug effects*
Tight Junctions / genetics
Toll-Like Receptor 9 / agonists
Up-Regulation
Zonula Occludens-1 Protein / genetics
Zonula Occludens-1 Protein / metabolism

Substances

Claudin-4
Interleukin-13
Oligodeoxyribonucleotides
ProMune
TJP1 protein, human
Toll-Like Receptor 9
Zonula Occludens-1 Protein