Loss of response to azacitidine is associated with deletion 12p13 in a patient with myelodysplastic syndrome with unique translocation t(13;17)(q12;q25) after prior breast cancer and acute promyelocytic leukemia

Ann Hematol. 2015 Sep;94(9):1617-9. doi: 10.1007/s00277-015-2428-6. Epub 2015 Jun 20.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antimetabolites, Antineoplastic* / administration & dosage
  • Antimetabolites, Antineoplastic* / adverse effects
  • Azacitidine* / administration & dosage
  • Azacitidine* / adverse effects
  • Breast Neoplasms* / drug therapy
  • Breast Neoplasms* / genetics
  • Breast Neoplasms* / pathology
  • Chromosome Deletion*
  • Chromosomes, Human, Pair 12 / genetics*
  • Chromosomes, Human, Pair 13 / genetics*
  • Drug Resistance, Neoplasm* / drug effects
  • Drug Resistance, Neoplasm* / genetics
  • Female
  • Humans
  • Leukemia, Promyelocytic, Acute* / chemically induced
  • Leukemia, Promyelocytic, Acute* / drug therapy
  • Leukemia, Promyelocytic, Acute* / genetics
  • Leukemia, Promyelocytic, Acute* / pathology
  • Middle Aged
  • Myelodysplastic Syndromes* / chemically induced
  • Myelodysplastic Syndromes* / genetics
  • Myelodysplastic Syndromes* / pathology
  • Neoplasms, Second Primary* / drug therapy
  • Neoplasms, Second Primary* / genetics
  • Neoplasms, Second Primary* / pathology
  • Translocation, Genetic*

Substances

  • Antimetabolites, Antineoplastic
  • Azacitidine