Artificial Lithium Toxicity: A Case Report and Review of the Literature

J Pharm Pract. 2015 Oct;28(5):479-81. doi: 10.1177/0897190015587698. Epub 2015 Jun 13.

Abstract

Lithium toxicity results in a range of gastrointestinal and neurologic signs and symptoms and can ultimately be fatal. Serum lithium levels may be unreliable when evaluating patients for toxicity, since levels may not be elevated in patients on chronic lithium therapy. Serum lithium levels may also be artificially elevated if blood is collected in a tube containing lithium heparin. We present a case of a woman on chronic lithium therapy whose lithium level was artificially elevated due to blood collection in an incorrect tube.

Keywords: critical care; drug information; nephrology; neurology; pharmacy education.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Blood Specimen Collection* / standards
  • Diagnostic Errors* / prevention & control
  • Female
  • Humans
  • Lithium Carbonate / blood*
  • Lithium Carbonate / therapeutic use
  • Psychotic Disorders / blood*
  • Psychotic Disorders / diagnosis
  • Psychotic Disorders / drug therapy

Substances

  • Lithium Carbonate