O-specific polysaccharides of Hafnia alvei lipopolysaccharides isolated from two serologically related strains: ATCC 13337 and 1187. A serological and structural study using chemical methods, gas chromatography/mass spectrometry and NMR spectroscopy at 500 MHz

Eur J Biochem. 1989 Dec 22;186(3):611-20. doi: 10.1111/j.1432-1033.1989.tb15251.x.

Abstract

The O-specific polysaccharides of Hafnia alvei ATCC 13337 standard strain and 1187 strain have been isolated and characterized. By means of 1H-NMR spectroscopy, methylation analysis and periodate oxidation, the repeating unit of the polysaccharides could be allocated the respective structures. (formula; see text) where Acyl = D-3-hydroxybutyryl, and 3-O-acetylation was to about 66%. The structural similarity of the polysaccharides was confirmed in the serological study; their epitopes were determined and the importance of various structural elements for the serological specificity was discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbohydrate Conformation
  • Carbohydrate Sequence
  • Enterobacteriaceae / immunology*
  • Gas Chromatography-Mass Spectrometry
  • Lipopolysaccharides*
  • Magnetic Resonance Spectroscopy
  • Methylation
  • Molecular Sequence Data
  • Polysaccharides / isolation & purification*

Substances

  • Lipopolysaccharides
  • Polysaccharides