Effects of endocytosis on receptor-mediated signaling

Roshanak Irannejad; Nikoleta G Tsvetanova; Braden T Lobingier; Mark von Zastrow

doi:10.1016/j.ceb.2015.05.005

Effects of endocytosis on receptor-mediated signaling

Curr Opin Cell Biol. 2015 Aug:35:137-43. doi: 10.1016/j.ceb.2015.05.005. Epub 2015 Jun 6.

Authors

Roshanak Irannejad¹, Nikoleta G Tsvetanova¹, Braden T Lobingier¹, Mark von Zastrow²

Affiliations

¹ Department of Psychiatry, University of California, San Francisco School of Medicine, 600 16th Street, San Francisco, CA 94158-2140, USA; Department of Cellular & Molecular Pharmacology, University of California, San Francisco School of Medicine, 600 16th Street, San Francisco, CA 94158-2140, USA.
² Department of Psychiatry, University of California, San Francisco School of Medicine, 600 16th Street, San Francisco, CA 94158-2140, USA; Department of Cellular & Molecular Pharmacology, University of California, San Francisco School of Medicine, 600 16th Street, San Francisco, CA 94158-2140, USA. Electronic address: mark.vonzastrow@ucsf.edu.

Abstract

Cellular mechanisms of membrane traffic and signal transduction are deeply interconnected. The present review discusses how membrane trafficking in the endocytic pathway impacts receptor-mediated signaling. Examples of recent progress are highlighted, focusing on the endocytosis-signaling nexus in mammals.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Biological Transport
Endocytosis*
Endosomes / metabolism
Humans
Signal Transduction* / physiology

Abstract

Publication types

MeSH terms

Grants and funding