[Treatment of vulvar intra-epithelial neoplasias with Imiquimod]

Gynecol Obstet Fertil. 2015 Jul-Aug;43(7-8):528-32. doi: 10.1016/j.gyobfe.2015.04.005. Epub 2015 Jun 3.
[Article in French]

Abstract

The incidence of vulvar intra-epithelial neoplasia (VIN) is increasing in the developed countries especially in young women. There is little consensus regarding the optimal management. Surgery used to be the gold standard. Alternatives to surgery are now needed for the treatment of VIN. Many studies investigated the effectiveness of Imiquimod 5% cream in this pathology. We present a literature review of the results published on the subject.

Keywords: HPV; Imiquimod; Néoplasie vulvaire intra-épithéliale; Traitement; Treatment; Vulvar intraepithelial neoplasia.

Publication types

  • Review

MeSH terms

  • Aminoquinolines / therapeutic use*
  • Antineoplastic Agents / therapeutic use*
  • Carcinoma in Situ / drug therapy*
  • Carcinoma in Situ / therapy
  • Female
  • Humans
  • Imiquimod
  • Treatment Outcome
  • Vulvar Neoplasms / drug therapy*
  • Vulvar Neoplasms / therapy

Substances

  • Aminoquinolines
  • Antineoplastic Agents
  • Imiquimod