[Spontaneous pneumothorax in patients with osteosarcoma treated by combined chemotherapy]

Minerva Med. 1989 Nov;80(11):1215-7.
[Article in Italian]

Abstract

A report is presented on 5 cases of pneumothorax which occurred during chemotherapy in patients suffering from osteogenic sarcoma of the extremities. None of them presented radiographically detectable substitutive pulmonary lesions. It was hypothesised that the origin of pneumothorax was the necrosis produced by agents of a pulmonary micrometastasis.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Bone Neoplasms / drug therapy*
  • Doxorubicin / administration & dosage
  • Extremities
  • Female
  • Humans
  • Leucovorin / administration & dosage
  • Lung Neoplasms / complications
  • Lung Neoplasms / secondary
  • Male
  • Methotrexate / administration & dosage
  • Osteosarcoma / drug therapy*
  • Osteosarcoma / secondary
  • Pneumothorax / etiology*
  • Time Factors
  • Vincristine / administration & dosage

Substances

  • Vincristine
  • Doxorubicin
  • Leucovorin
  • Methotrexate