Validation of the Chinese version of the Neurological Disorders Depression Inventory for Epilepsy (C-NDDI-E) in West China

Xin Tong; Dongmei An; Lili Lan; Xiaobo Zhou; Qin Zhang; Fenglai Xiao; Sung-Pa Park; Kousuke Kanemoto; Andres M Kanner; Dong Zhou

doi:10.1016/j.yebeh.2015.03.012

Validation of the Chinese version of the Neurological Disorders Depression Inventory for Epilepsy (C-NDDI-E) in West China

Epilepsy Behav. 2015 Jun:47:6-10. doi: 10.1016/j.yebeh.2015.03.012. Epub 2015 May 21.

Authors

Xin Tong¹, Dongmei An², Lili Lan³, Xiaobo Zhou⁴, Qin Zhang⁵, Fenglai Xiao⁶, Sung-Pa Park⁷, Kousuke Kanemoto⁸, Andres M Kanner⁹, Dong Zhou¹⁰

Affiliations

¹ Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: saratx@163.com.
² Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: andongmei2010@gmail.com.
³ Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China. Electronic address: lllxiya@126.com.
⁴ Department of Psychiatry, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: zhouxiaobo19861986@163.com.
⁵ Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: qinqin198@163.com.
⁶ Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: fenglaixiao@gmail.com.
⁷ Department of Neurology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea. Electronic address: sppark@knu.ac.kr.
⁸ Department of Neuropsychiatry, School of Medicine, Aichi Medical University, Nagakute, Japan. Electronic address: fwkh2919@mb.infoweb.ne.jp.
⁹ Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA. Electronic address: a.kanner@med.miami.edu.
¹⁰ Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: zhoudong66@yahoo.de.

PMID: 26004785
DOI: 10.1016/j.yebeh.2015.03.012

Abstract

Objective: We aimed to validate the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) for Chinese people with epilepsy (PWE).

Methods: The NDDI-E was translated into a Chinese version. A consecutive cohort of PWE from West China Hospital was recruited to test the reliability and validity of the Chinese version of the NDDI-E (C-NDDI-E). Each patient underwent the Mini International Neuropsychiatric Interview (MINI) and C-NDDI-E.

Results: A total of 202 PWE completed the psychiatric evaluation. The C-NDDI-E was easily comprehended and quickly completed by all participants. Fifty-four patients (26.7%) had current major depressive disorder (MDD) according to the MINI criteria. The Cronbach's α coefficient for the C-NDDI-E was 0.825. Receiver operating characteristic analyses showed an area under the curve of 0.936 (95% CI=0.904-0.968). At a cutoff score of >12, the C-NDDI-E had a sensitivity of 0.926, a specificity of 0.804, a positive predictive value of 0.633, and a negative predictive value of 0.967.

Conclusion: The C-NDDI-E is a valuable instrument for screening MDD in Chinese PWE.

Keywords: China; Depression; Epilepsy; NDDI-E; Validation.

MeSH terms

Adult
Asian People* / ethnology
Asian People* / psychology
China
Depression / diagnosis*
Depression / ethnology
Depression / psychology
Depressive Disorder, Major / diagnosis*
Depressive Disorder, Major / ethnology
Depressive Disorder, Major / psychology
Epilepsy / diagnosis*
Epilepsy / ethnology
Epilepsy / psychology
Female
Hospitals
Humans
Language
Male
Nervous System Diseases / diagnosis*
Nervous System Diseases / ethnology
Nervous System Diseases / psychology
Neuropsychological Tests
Personality Inventory / standards
Psychiatric Status Rating Scales / standards*
ROC Curve
Reproducibility of Results
Sensitivity and Specificity
Translating