Baclofen overdose from possible intrinsic malfunction of SynchroMed II pump

J Neurosurg Pediatr. 2015 Aug;16(2):232-4. doi: 10.3171/2015.1.PEDS14500. Epub 2015 May 15.

Abstract

This is a case report illustrating an overdose of baclofen in a 10-year-old boy due to a likely malfunction of a SynchroMed II pump. This ultimately necessitated a pump replacement. One-year follow-up showed no further incidents of baclofen overdose, with multiple pump refills.

Keywords: baclofen; functional neurosurgery; overdose; pump.

MeSH terms

  • Baclofen / administration & dosage*
  • Cerebral Palsy / drug therapy*
  • Cerebral Palsy / etiology
  • Child
  • Device Removal
  • Drug Overdose / etiology*
  • Drug Overdose / therapy
  • Equipment Failure
  • GABA-B Receptor Agonists / administration & dosage*
  • Humans
  • Infusion Pumps, Implantable / adverse effects*
  • Infusions, Spinal
  • Leukomalacia, Periventricular / complications
  • Male
  • Recurrence

Substances

  • GABA-B Receptor Agonists
  • Baclofen