The impact of PCR in the management of prosthetic joint infections

Expert Rev Mol Diagn. 2015;15(7):957-64. doi: 10.1586/14737159.2015.1046437. Epub 2015 May 12.

Abstract

An accurate diagnosis of prosthetic joint infection (PJI) remains a challenging clinical problem and is essential for the success of treatment regardless of the treatment option chosen by patients and surgeons. In recent years, PCR for the diagnosis of PJI has received much attention. Here, we review the impact of common PCR-based techniques on identifying causative organisms, antibiotic management and economics of PJI.

Keywords: 16S PCR; PCR; PJI; prosthetic joint; sonication.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / therapeutic use
  • Arthritis, Infectious / diagnosis*
  • Arthritis, Infectious / drug therapy
  • Arthritis, Infectious / microbiology
  • Disease Management
  • Humans
  • Polymerase Chain Reaction / economics
  • Polymerase Chain Reaction / methods*
  • Polymerase Chain Reaction / standards
  • Prosthesis-Related Infections / diagnosis*
  • Prosthesis-Related Infections / drug therapy
  • Prosthesis-Related Infections / microbiology
  • Sensitivity and Specificity

Substances

  • Anti-Infective Agents