B-type natriuretic peptide may be unsuitable for diagnosing central acute pulmonary embolism

Indian J Chest Dis Allied Sci. 2014 Oct-Dec;56(4):253-4.

Abstract

We describe a case of a 90-year-old male admitted to the emergency department with deep vein thrombosis and central acute pulmonary embolism. Despite a remarkably increased value of D-dimer and a modestly elevated concentration of cardiac troponin I, the value of B-type natriuretic peptide was found to be non-diagnostic. Limited to this single case report, our evidence suggests that the measurement of natriuretic peptides is questionable for diagnosing central acute pulmonary embolism in the emergency department.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anticoagulants / administration & dosage
  • Diagnosis, Differential
  • Fibrin Fibrinogen Degradation Products / analysis
  • Heparin, Low-Molecular-Weight / administration & dosage*
  • Humans
  • Male
  • Natriuretic Peptide, Brain / blood*
  • Predictive Value of Tests
  • Prognosis
  • Pulmonary Embolism* / blood
  • Pulmonary Embolism* / diagnosis
  • Pulmonary Embolism* / drug therapy
  • Pulmonary Embolism* / etiology
  • Reproducibility of Results
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome
  • Troponin I / blood
  • Venous Thrombosis / complications*
  • Warfarin / administration & dosage*

Substances

  • Anticoagulants
  • Fibrin Fibrinogen Degradation Products
  • Heparin, Low-Molecular-Weight
  • Troponin I
  • fibrin fragment D
  • Natriuretic Peptide, Brain
  • Warfarin