Kikuchi disease preceding systemic lupus erythematosus with membranous lupus nephritis

NDT Plus. 2009 Oct;2(5):370-2. doi: 10.1093/ndtplus/sfp090. Epub 2009 Jul 17.

Abstract

Kikuchi disease (KD) is a rare form of necrotizing lymphadenitis. KD usually presents with cervical lymphadenopathy and fever in young women. It tends to run a benign course and resolve spontaneously within months. The aetiology of the disease is still unclear although a variety of infectious agents have been postulated. There is also a documented but rare association with systemic lupus erythematosus (SLE). We present the case of a young woman with biopsy-proven KD who subsequently developed SLE with biopsy-proven lupus nephritis. Nephrologists should be aware of KD as it may precede the development of SLE and lupus nephritis.

Keywords: Kikuchi disease; lupus nephritis; systemic lupus erythematosus.

Publication types

  • Case Reports