Assessing prevention measures and Sin Nombre hantavirus seroprevalence among workers at Yosemite National Park

Am J Ind Med. 2015 Jun;58(6):658-67. doi: 10.1002/ajim.22445. Epub 2015 May 5.

Abstract

Background: During 2012, a total of 10 overnight visitors to Yosemite National Park (Yosemite) became infected with a hantavirus (Sin Nombre virus [SNV]); three died. SNV infections have been identified among persons with occupational exposure to deer mice (Peromyscus maniculatus).

Methods: We assessed SNV infection prevalence, work and living environments, mice exposures, and SNV prevention training, knowledge, and practices among workers of two major employers at Yosemite during September-October, 2012 by voluntary blood testing and a questionnaire.

Results: One of 526 participants had evidence of previous SNV infection. Participants reported frequently observing rodent infestations at work and home and not always following prescribed safety practices for tasks, including infestation cleanup.

Conclusion: Although participants had multiple exposures to deer mice, we did not find evidence of widespread SNV infections. Nevertheless, employees working around deer mice should receive appropriate training and consistently follow prevention policies for high-risk activities.

Keywords: Sin Nombre virus; disease transmission; hantavirus; infectious; occupational health.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antibodies, Viral / blood*
  • California
  • Hantavirus Pulmonary Syndrome / blood*
  • Hantavirus Pulmonary Syndrome / prevention & control
  • Hantavirus Pulmonary Syndrome / psychology
  • Hantavirus Pulmonary Syndrome / transmission
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Occupational Diseases / blood*
  • Occupational Diseases / prevention & control
  • Occupational Diseases / psychology
  • Occupational Exposure / prevention & control
  • Parks, Recreational
  • Peromyscus / virology*
  • Seroepidemiologic Studies
  • Sin Nombre virus / immunology*
  • Surveys and Questionnaires

Substances

  • Antibodies, Viral