New method for the rapid extraction of natural products: efficient isolation of shikimic acid from star anise

Org Lett. 2015 May 15;17(10):2428-30. doi: 10.1021/acs.orglett.5b00936. Epub 2015 May 4.

Abstract

A new, practical, rapid, and high-yielding process for the pressurized hot water extraction (PHWE) of multigram quantities of shikimic acid from star anise (Illicium verum) using an unmodified household espresso machine has been developed. This operationally simple and inexpensive method enables the efficient and straightforward isolation of shikimic acid and the facile preparation of a range of its synthetic derivatives.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biological Products / chemistry
  • Biological Products / isolation & purification*
  • Illicium / chemistry*
  • Molecular Conformation
  • Shikimic Acid / chemistry
  • Shikimic Acid / isolation & purification*

Substances

  • Biological Products
  • Shikimic Acid