[Chemotherapy-induced cardiotoxicity: Incidence, diagnosis and prevention]

Bull Cancer. 2015 Jul-Aug;102(7-8):622-6. doi: 10.1016/j.bulcan.2015.03.014. Epub 2015 Apr 29.
[Article in French]

Abstract

Chemotherapy-induced cardiotoxicity is a major cause of morbidity and mortality in cancer survivor. The most clinically evident and best known cardiotoxicity is the anthracycline adverse effect with heart failure. Many cardiovascular adverse effects appear after cancer therapy: heart congestive failure, myocardial ischemia, hypertension, thromboembolic complications, arrhythmias and conduction disturbances. There are potential strategies to mitigate the risks of cardiac complications for cancer patients with physical examination, echocardiography and electrocardiogram. The management of the cardiotoxicity is variable.

Keywords: Cardiotoxicity; Cardiotoxicité; Chemotherapy; Children; Chimiothérapie; Enfant.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Anthracyclines / adverse effects
  • Antibiotics, Antineoplastic / adverse effects
  • Antineoplastic Agents / adverse effects*
  • Arrhythmias, Cardiac / chemically induced
  • Cardiomyopathy, Dilated / chemically induced
  • Cardiotoxicity
  • Child, Preschool
  • Heart Diseases / chemically induced*
  • Heart Diseases / diagnosis
  • Heart Diseases / prevention & control
  • Heart Failure / chemically induced
  • Heart Failure / diagnosis
  • Heart Failure / prevention & control
  • Humans
  • Hypertension / chemically induced
  • Incidence
  • Myocardial Ischemia / chemically induced
  • Thromboembolism / chemically induced

Substances

  • Anthracyclines
  • Antibiotics, Antineoplastic
  • Antineoplastic Agents