Ultrasound Elastography and MR Elastography for Assessing Liver Fibrosis: Part 2, Diagnostic Performance, Confounders, and Future Directions

AJR Am J Roentgenol. 2015 Jul;205(1):33-40. doi: 10.2214/AJR.15.14553. Epub 2015 Apr 23.

Abstract

Objective: The purpose of the article is to review the diagnostic performance of ultra-sound and MR elastography techniques for detection and staging of liver fibrosis, the main current clinical applications of elastography in the abdomen.

Conclusion: Technical and instrument-related factors and biologic and patient-related factors may constitute potential confounders of stiffness measurements for assessment of liver fibrosis. Future developments may expand the scope of elastography for monitoring liver fibrosis and predict complications of chronic liver disease.

Keywords: MR elastography (MRE); MRI; elasticity; elastography; liver fibrosis; ultrasound; viscosity.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diagnosis, Differential
  • Elastic Modulus
  • Elasticity Imaging Techniques / methods*
  • Elasticity Imaging Techniques / trends
  • Forecasting
  • Humans
  • Liver Cirrhosis / diagnosis*
  • Liver Cirrhosis / diagnostic imaging
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Imaging / trends
  • Viscosity