New beam monitoring tool for radiobiology experiments at the cyclotron ARRONAX

Radiat Prot Dosimetry. 2015 Sep;166(1-4):257-60. doi: 10.1093/rpd/ncv199. Epub 2015 Apr 20.

Abstract

The ARRONAX cyclotron is able to deliver alpha particles at 68 MeV. In the frame of radiological research, a new method is studied to infer in situ the deposited dose: it is based on the online measurement of the bremsstrahlung (>1 keV) produced by the interaction of the incident particle with the medium. Experiments are made using bombarded poly(methyl methacrylate) (PMMA)-equivalent water targets in order to characterise this continuous X-ray spectrum. The intensity of the bremsstrahlung spectrum allows for the beam monitoring. A simulation code of the bremsstrahlung has been built, and a good agreement is found with the experimental spectra. With this simulation, it is possible to predict the sensibility of this method: it varies with the target thickness, showing a good sensibility for thin target (<1000 µm) and saturation for thicker ones. Bremsstrahlung spectrum also shows a sensibility on the target's chemical composition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alpha Particles
  • Computer Simulation
  • Cyclotrons / instrumentation*
  • Models, Theoretical*
  • Monte Carlo Method
  • Photons
  • Polymethyl Methacrylate / chemistry
  • Polymethyl Methacrylate / radiation effects*
  • Radiobiology*
  • Radiotherapy Planning, Computer-Assisted / instrumentation*
  • X-Rays

Substances

  • Polymethyl Methacrylate