[Survival among renal allograft recipients from non related living donors]

Rev Med Chil. 2015 Feb;143(2):147-57. doi: 10.4067/S0034-98872015000200001.
[Article in Spanish]

Abstract

Background: There is a gap between the number of patients requiring a renal allograft and the number of potential deceased donors (DD). One alternative is using allografts from non-related living donors (NRLD).

Aim: To compare survival and complications of renal allograft recipients from DD, related living donors (RLD) and NRLD.

Material and methods: Observational study of a cohort of renal allograft recipients. Of 253 transplants performed in a Chilean region between 1981 and 2003, 20 patients received and allograft from a NRLD. Graft and patient survival of these patients were compared with those of 93 patients receiving an allograft from a related living donor and 140 receiving it from a DD. Patients were followed for 10 years or until death or dialysis requirement.

Results: No significant differences between groups in graft and patient survival, deaths with a functioning graft or return to dialysis were observed. Receptors of DD had more hospital admissions during the first years after receiving the graft, usually due to infections. Also a delayed graft function was more common among them. Glomerular filtration rate ten years after the graft was similar among the three groups.

Conclusions: No differences in graft or patient survival was observed between patients receiving a renal allograft from NRLD, RLD or DD.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Allografts / statistics & numerical data*
  • Cause of Death
  • Chile / epidemiology
  • Female
  • Follow-Up Studies
  • Glomerular Filtration Rate / physiology
  • Graft Survival / physiology*
  • Hospitalization / statistics & numerical data
  • Humans
  • Immunosuppression Therapy / statistics & numerical data
  • Infections / complications
  • Kidney Transplantation / adverse effects
  • Kidney Transplantation / mortality*
  • Living Donors*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Survival Rate
  • Time Factors
  • Unrelated Donors / statistics & numerical data*
  • Young Adult