Invariant natural killer T cells treated with rapamycin or transforming growth factor-β acquire a regulatory function and suppress T effector lymphocytes

Cell Mol Immunol. 2017 Apr;14(4):392-394. doi: 10.1038/cmi.2015.20. Epub 2015 Apr 6.

Authors

Giuliana Guggino¹, Cristiano Scottà², Giovanna Lombardi², Francesco Dieli¹, Guido Sireci¹

Affiliations

¹ Dipartimento di Biopatologia e Biotecnologie Mediche, University of Palermo, Palermo, Italy.
² Department of Immunoregulation and Immune Intervention, King's College London, London, UK.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Humans
Mice
Natural Killer T-Cells / drug effects
Natural Killer T-Cells / immunology*
Sirolimus / pharmacology*
T-Lymphocytes, Regulatory / drug effects
T-Lymphocytes, Regulatory / immunology*
Transforming Growth Factor beta / pharmacology*

Substances

Transforming Growth Factor beta
Sirolimus