Susceptibility to Measles Among Perinatally HIV-Infected Adolescents and Young Adults

J Pediatric Infect Dis Soc. 2015 Mar;4(1):63-6. doi: 10.1093/jpids/pit054. Epub 2013 Sep 24.

Abstract

Among our cohort of adolescents and young adults with perinatally acquired human immunodeficiency virus, few (17.6%) had measles protective antibodies by plaque reduction neutralization (PRN). Agreement was demonstrated between the commercial enzyme immunoassay and the PRN assay (K = 0.59 [95% confidence interval: 0.23-0.95]). Further studies are needed to understand the determinants of immunity in this population.

Keywords: HIV; adolescents; measles immunity; perinatally acquired HIV infection..

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Anti-Retroviral Agents / therapeutic use
  • Cohort Studies
  • Disease Susceptibility*
  • Female
  • HIV Infections / drug therapy
  • HIV Infections / epidemiology*
  • HIV Infections / immunology*
  • Humans
  • Immunoenzyme Techniques
  • Male
  • Measles / epidemiology*
  • Measles / immunology*
  • Young Adult

Substances

  • Anti-Retroviral Agents