Comparison of Lotrafilcon B and Balafilcon A silicone hydrogel bandage contact lenses in reducing pain and discomfort after photorefractive keratectomy: A contralateral eye study

Cont Lens Anterior Eye. 2015 Jun;38(3):211-4. doi: 10.1016/j.clae.2015.01.014. Epub 2015 Apr 2.

Abstract

Purpose: To assess the effect of two silicone hydrogel contact lenses with high oxygen permeability in patients having photorefractive keratectomy (PRK).

Setting: Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Methods: Sixty patients (120 eyes) who had bilateral PRK were enrolled in this double blind clinical trial. Each patient was fitted with a Lotrafilcon B (Air Optix(®)AQUA, Ciba Vision, Duluth, GA, USA) lens in one eye and a Balafilcon A (PureVision™ Bausch & Lomb, Rochester, NY, USA) lens in the fellow eye. Patients' responses to a subjective questionnaire in terms of pain, foreign body sensation, photophobia, blurred vision and epiphora were evaluated on the first and third postoperative days.

Results: Mean pain score for Lotrafilcon B and Balafilcon A contact lenses was 4.43±3.18 vs. 5.45±3.37 on the first postoperative day and 3.43±3.23 vs. 3.88±3.01 on the third postoperative day. However, the difference was only significant in the first 24h after surgery (P=0.032). Foreign body sensation was clinically higher with Balafilcon A contact lens (5.0±3.47 vs. 4.08±3.34 on day 1 and 4.98±3.52 vs. 3.55±3.20 on day 3) and the difference was statistically significant on the first and the third postoperative days (P=0.042 and 0.002, respectively). There was no statistically significant difference between two contact lenses in terms of photophobia, epiphora and blurred vision (P>0.05).

Conclusion: The Lotrafilcon B lens resulted in significantly less postoperative pain and discomfort after PRK, especially in the first 24h after PRK.

Keywords: Bandage contact lens; Photorefractive keratectomy; Silicone hydrogel contact lens.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Bandages, Hydrocolloid*
  • Contact Lenses, Hydrophilic*
  • Double-Blind Method
  • Female
  • Follow-Up Studies
  • Humans
  • Hydrogels / administration & dosage*
  • Male
  • Middle Aged
  • Myopia / surgery*
  • Pain, Postoperative / drug therapy*
  • Photorefractive Keratectomy / adverse effects*
  • Photorefractive Keratectomy / methods
  • Retrospective Studies
  • Silicones / administration & dosage*
  • Young Adult

Substances

  • Hydrogels
  • Silicones
  • balafilcon A
  • lotrafilcon B