When to offer genetic testing for pulmonary arterial hypertension

Wendy K Chung; Eric D Austin; D Hunter Best; Lynette M Brown; C Gregory Elliott

doi:10.1016/j.cjca.2014.11.005

When to offer genetic testing for pulmonary arterial hypertension

Can J Cardiol. 2015 Apr;31(4):544-7. doi: 10.1016/j.cjca.2014.11.005. Epub 2014 Nov 11.

Authors

Wendy K Chung¹, Eric D Austin², D Hunter Best³, Lynette M Brown⁴, C Gregory Elliott⁵

Affiliations

¹ Departments of Pediatrics and Medicine, Columbia University Medical Center, New York, New York, USA.
² Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
³ Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah and ARUP Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, Utah, USA.
⁴ Department of Medicine, Intermountain Medical Center, Murray, Utah and Department of Medicine, the University of Utah School of Medicine, Salt Lake City, Utah, USA.
⁵ Department of Medicine, Intermountain Medical Center, Murray, Utah and Department of Medicine, the University of Utah School of Medicine, Salt Lake City, Utah, USA. Electronic address: greg.elliott@imail.org.

Abstract

Genetic testing is poised to play a greater role in the diagnosis and management of pulmonary arterial hypertension (PAH). Physicians who manage PAH should know the heritable PAH phenotypes, inheritance patterns, and responsible genes. They also should know indications, potential risks and benefits, and the issues surrounding genetic counselling and testing for patients with PAH.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Genetic Counseling / methods*
Genetic Testing / methods*
Humans
Hypertension, Pulmonary / diagnosis*
Hypertension, Pulmonary / genetics*
Time Factors

Abstract

Publication types

MeSH terms

Grants and funding