Caging the elephant: selective autophagy tackles giant intracellular protein crystals

Sabrina Habisov; Vladimir Kirkin

doi:10.1016/j.molcel.2015.03.022

Caging the elephant: selective autophagy tackles giant intracellular protein crystals

Mol Cell. 2015 Apr 2;58(1):5-7. doi: 10.1016/j.molcel.2015.03.022.

Authors

Sabrina Habisov¹, Vladimir Kirkin²

Affiliations

¹ Merck KGaA, Frankfurter Strasse 250, 64293 Darmstadt, Germany; BMLS Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany.
² Merck KGaA, Frankfurter Strasse 250, 64293 Darmstadt, Germany. Electronic address: vladimir.kirkin@merckgroup.com.

PMID: 25839431
DOI: 10.1016/j.molcel.2015.03.022

Abstract

In this issue of Molecular Cell, Tsutsui et al. (2015) show that in vivo protein crystallization may come in handy not only when solving the structure of a protein, but also when studying molecular mechanisms of selective autophagy.

Publication types

Comment

MeSH terms

Animals
Anthozoa / chemistry*
Cytosol / metabolism*
Green Fluorescent Proteins / chemistry*
Humans
Lysosomes / metabolism*

Substances

Green Fluorescent Proteins