Surgical results of trabeculectomy and Ahmed valve implantation following a previous failed trabeculectomy in primary congenital glaucoma patients

Korean J Ophthalmol. 2015 Apr;29(2):109-14. doi: 10.3341/kjo.2015.29.2.109. Epub 2015 Mar 17.

Abstract

Purpose: To compare the surgical results of trabeculectomy and Ahmed glaucoma valve implantation after a previous failed trabeculectomy.

Methods: A retrospective comparative case series review was performed on 31 eye surgeries in 20 patients with primary congenital glaucoma who underwent trabeculectomy or Ahmed glaucoma valve implantation after a previous failed trabeculectomy with mitomycin C.

Results: The preoperative mean intraocular pressure was 25.5 mmHg in the trabeculectomy group and 26.9 mmHg in the Ahmed glaucoma valve implantation group (p = 0.73). The 48-month postoperative mean intraocular pressure was 19.6 mmHg in the trabeculectomy group and 20.2 mmHg in the Ahmed glaucoma valve implantation group (p = 0.95). The 12-month trabeculectomy success rate was 69%, compared with 64% for Ahmed glaucoma valve implantation, and the 48-month success rates were 42% and 36% for trabeculectomy and valve implantation, respectively. The success rates following the entire follow-up period were not significantly different between the two groups (p > 0.05 by log rank test). Postoperative complications occurred in 25% of the trabeculectomy-operated eyes and 9% of the Ahmed-implanted eyes (p = 0.38).

Conclusions: There was no significant difference in surgical outcome between the trabeculectomy and Ahmed glaucoma valve implantation groups, neither of which had favorable results. However, the trabeculectomy group demonstrated a higher prevalence of adverse complications such as post-operative endophthalmitis.

Keywords: Ahmed valve implantation; Congenital glaucoma; Surgical outcomes; Trabeculectomy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Glaucoma / congenital
  • Glaucoma / physiopathology
  • Glaucoma / surgery*
  • Glaucoma Drainage Implants*
  • Humans
  • Infant
  • Intraocular Pressure / physiology*
  • Male
  • Mitomycin / adverse effects*
  • Nucleic Acid Synthesis Inhibitors / adverse effects
  • Reoperation
  • Retrospective Studies
  • Time Factors
  • Trabeculectomy / adverse effects*
  • Trabeculectomy / methods*
  • Treatment Failure
  • Treatment Outcome
  • Visual Acuity*

Substances

  • Nucleic Acid Synthesis Inhibitors
  • Mitomycin