Clinical trial design of serious gaming in mild cognitive impairment

Front Aging Neurosci. 2015 Mar 11:7:26. doi: 10.3389/fnagi.2015.00026. eCollection 2015.

¹ Fondazione Europea Ricerca Biomedica, Centro Eccellenza Alzheimer Ospedale Briolini, Bergamo, Italy ; Department of Molecular and Translational Medicine, University of Brescia Brescia, Italy.
² Division of Neurology V/Neuropathology, Fondazione IRCCS Istituto Neurologico "Carlo Besta" Milan, Italy.
³ Fondazione Poliambulanza, Nuclear Medicine Department Brescia, Italy.
⁴ Fondazione Europea Ricerca Biomedica, Centro Eccellenza Alzheimer Ospedale Briolini, Bergamo, Italy.
⁵ Laboratory of Epidemiology, Neuroimaging and Telemedicine, IRCCS Centro San Giovanni di Dio-Fatebenefratelli Brescia, Italy ; Memory Clinic and LANVIE - Laboratory of Neuroimaging of Aging, University Hospitals and University of Geneva Geneva, Switzerland.

No abstract available

Keywords: Alzheimer's disease; biomarker enrichment strategy; clinical trials; mild cognitive impairment; outcome measures; serious games.