Rotavirus seasonal distribution and prevalence before and after the introduction of rotavirus vaccine in a peri-urban community of Lima, Peru

Am J Trop Med Hyg. 2015 May;92(5):986-8. doi: 10.4269/ajtmh.14-0431. Epub 2015 Mar 16.

Abstract

We evaluated the monthly distribution of rotavirus diarrhea in a cohort of children 12-24 months of age followed as part of a diarrhea clinical trial in a peri-urban community of Lima. We observed a peak of rotavirus diarrhea in the winter months and a decrease in rotavirus prevalence after the introduction of the rotavirus vaccine in Peru.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Anti-Infective Agents / therapeutic use
  • Child, Preschool
  • Cohort Studies
  • Diarrhea / epidemiology*
  • Diarrhea / prevention & control*
  • Diarrhea / virology
  • Double-Blind Method
  • Female
  • Humans
  • Incidence
  • Infant
  • Lactoferrin / therapeutic use
  • Male
  • Peru / epidemiology
  • Prevalence
  • Residence Characteristics
  • Rotavirus / immunology*
  • Rotavirus / isolation & purification
  • Rotavirus Infections / epidemiology*
  • Rotavirus Infections / prevention & control*
  • Rotavirus Infections / virology
  • Rotavirus Vaccines / administration & dosage*
  • Seasons

Substances

  • Anti-Infective Agents
  • Rotavirus Vaccines
  • Lactoferrin