Superhydrophobic Surfaces as a Tool for the Fabrication of Hierarchical Spherical Polymeric Carriers

Small. 2015 Aug 12;11(30):3648-52. doi: 10.1002/smll.201500192. Epub 2015 Mar 12.

Abstract

Hierarchical polymeric carriers with high encapsulation efficiencies are fabricated via a biocompatible strategy developed using superhydrophobic (SH) surfaces. The carries are obtained by the incorporation of cell/BSA-loaded dextran-methacrylate (DEXT-MA) microparticles into alginate (ALG) macroscopic beads. Engineered devices like these are expected to boost the development of innovative and customizable systems for biomedical and biotechnological purposes.

Keywords: biomaterials; cell encapsulation; drug delivery; hierarchical carriers; superhydrophobic surfaces.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Transplantation / methods*
  • Hydrophobic and Hydrophilic Interactions*
  • Materials Testing
  • Nanocapsules / chemistry*
  • Nanocapsules / ultrastructure
  • Nanospheres / chemistry*
  • Nanospheres / ultrastructure
  • Particle Size
  • Surface Properties

Substances

  • Nanocapsules