Classic biphasic pulmonary blastoma with brain and axillary metastases: a case report with molecular analysis and review of literature

Int J Clin Exp Pathol. 2015 Jan 1;8(1):983-8. eCollection 2015.

Abstract

Pulmonary blastoma is a rare series of malignant lung tumor, which contains three categories: classic biphasic pulmonary blastoma, pluropulmonary blastoma, and well-differentiated fetal adenocarcinoma. In this study, a 19-year old female suffering with classic biphasic pulmonary blastoma and metastases in brain and axilla was presented with special interest in clinicopathological presentations, immunohistochemical features, and molecular characterizations. However, this case was misdiagnosed initially with small biopsy specimen. Comprehensive management should be used for the treatment of this malignancy.

Keywords: Pulmonary blastoma; classic biphasic pulmonary blastoma; metastasis; treatment.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Axilla / pathology
  • Biomarkers, Tumor / analysis
  • Brain Neoplasms / secondary
  • Female
  • Humans
  • Immunohistochemistry
  • Lung Neoplasms / pathology*
  • Lymphatic Metastasis / pathology
  • Pulmonary Blastoma / secondary*
  • Young Adult

Substances

  • Biomarkers, Tumor