Childhood obesity is one of the most important issues in Public Health so that the adoption of innovative preventive integrated approaches is increasingly needed. The presence of coordinated and integrated programmes, aimed at preventing childhood obesity and based on innovative large-scale approaches, was ascertained by means of a literature search. In Europe three programmes, with activities and staff characterized by common aims and active participation of different stakeholders, use such a community-based approach, which allowed changes in physical and social environment, resulting in new and innovative elements for lifestyle modifications.