Plasma polymerised polyoxazoline thin films for biomedical applications

Chem Commun (Camb). 2015 Mar 11;51(20):4279-82. doi: 10.1039/c5cc00260e.

Abstract

Poly(2-oxazoline)s are emerging revolutionary biomaterials, exhibiting comparable and even superior properties to well-established counterparts. Overcoming current tedious wet synthesis methods, we report solvent-free and substrate independent, plasma polymerised nanoscale biocompatible polyoxazoline coatings capable of controlling protein and cell adhesion, and significantly reducing biofilm build up.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials / chemistry*
  • Biocompatible Materials / pharmacology
  • Cell Adhesion
  • Cell Survival
  • Cells, Cultured
  • Fibroblasts / drug effects
  • Fibroblasts / metabolism
  • Humans
  • Interleukin-6 / metabolism
  • Macrophages / drug effects
  • Oxazoles / chemistry*
  • Oxazoles / pharmacology
  • Polyamines / chemistry
  • Polymerization
  • Serum Albumin, Bovine / chemistry
  • Tumor Necrosis Factor-alpha / metabolism

Substances

  • Biocompatible Materials
  • IL6 protein, human
  • Interleukin-6
  • Oxazoles
  • Polyamines
  • Tumor Necrosis Factor-alpha
  • poly(2-oxazoline)
  • Serum Albumin, Bovine
  • polyallylamine