Prevalence and macrolide resistance of Mycoplasma genitalium in South African women

Sex Transm Dis. 2015 Mar;42(3):140-2. doi: 10.1097/OLQ.0000000000000246.

Abstract

Remnant specimens from 601 women obtained in a cross-sectional study from rural South Africa were tested for Mycoplasma genitalium. Overall, 10.8% of women were infected with M. genitalium either in the vagina or in the rectum. Macrolide resistance, although of low prevalence, in M. genitalium is described for the first time in Sub-Saharan Africa.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Bacterial Agents / pharmacology*
  • Cervix Uteri / microbiology*
  • Cross-Sectional Studies
  • DNA, Bacterial / drug effects
  • Drug Resistance, Bacterial / genetics*
  • Female
  • Humans
  • Middle Aged
  • Mycoplasma Infections / epidemiology
  • Mycoplasma Infections / genetics*
  • Mycoplasma Infections / microbiology
  • Mycoplasma genitalium / genetics*
  • Mycoplasma genitalium / isolation & purification
  • Point Mutation
  • Prevalence
  • RNA, Ribosomal, 23S / genetics
  • Real-Time Polymerase Chain Reaction
  • Rectum / microbiology*
  • Risk Factors
  • Sequence Analysis, DNA
  • South Africa / epidemiology
  • Vagina / microbiology*

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • RNA, Ribosomal, 23S