Multifocal phaeohyphomycosis caused by Exophiala xenobiotica in a kidney transplant recipient

Transpl Infect Dis. 2015 Apr;17(2):297-302. doi: 10.1111/tid.12350. Epub 2015 Feb 5.

Abstract

In recent years, black fungi have been increasingly reported as causing opportunistic infections after solid organ transplantation. Here, we report a case of insidious, relentless, and multifocal Exophiala xenobiotica infection in a kidney transplant recipient that eventually required multiple surgical excisions along with oral and intravenous antifungal combination therapy using liposomal amphotericin B and posaconazole. We compare the present case with all previously reported cases of Exophiala infection after kidney transplantation.

Keywords: Exophiala; antimycotic therapy; black fungi; kidney transplant recipient; phaeohyphomycosis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Exophiala*
  • Female
  • Graft Rejection / prevention & control*
  • Humans
  • Immunocompromised Host*
  • Immunosuppressive Agents / adverse effects*
  • Kidney Transplantation*
  • Opportunistic Infections / etiology*
  • Opportunistic Infections / immunology
  • Opportunistic Infections / pathology
  • Phaeohyphomycosis / etiology*
  • Phaeohyphomycosis / immunology
  • Phaeohyphomycosis / pathology
  • Transplant Recipients

Substances

  • Immunosuppressive Agents