Rationales that providers and family members cited for the use of antipsychotic medications in nursing home residents with dementia

J Am Geriatr Soc. 2015 Feb;63(2):302-8. doi: 10.1111/jgs.13230. Epub 2015 Jan 30.

Abstract

Objectives: To describe the rationales that providers and family members cite for the use of antipsychotic medications in people with dementia living in nursing homes (NHs).

Design: Qualitative, descriptive study.

Setting: Twenty-six medium-sized and large facilities in five Centers for Medicare and Medicaid Services regions.

Participants: Individuals diagnosed with dementia who received an antipsychotic medication.

Measurements: Data were collected from medical record abstraction and interviews with prescribers, administrators, direct care providers, and family members. Textual data from medical record abstraction and responses to open-ended interview questions were analyzed using directed content analysis techniques. A coding scheme was developed, and coded reasons for antipsychotic prescribing were summarized across all sources.

Results: Major categories of reasons for use of antipsychotic medications in the 204 NH residents in the study sample were behavioral (n = 171), psychiatric (n = 159), emotional states (n = 105), and cognitive diagnoses or symptoms (n = 114). The most common behavioral reasons identified were verbal (n = 91) and physical (n = 85) aggression. For the psychiatric category, psychosis (n = 95) was most frequently described. Anger (n = 93) and sadness (n = 20) were the most common emotional states cited.

Conclusion: The rationale for use of antipsychotic drug therapy frequently relates to a wide variety of indications for which these drugs are not approved and for which evidence of efficacy is lacking. These findings have implications for clinical practice and policy.

Keywords: antipsychotic medication; dementia; nursing home.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antipsychotic Agents / therapeutic use*
  • Dementia / drug therapy*
  • Dementia / psychology
  • Family / psychology*
  • Female
  • Health Facility Size
  • Health Personnel / psychology*
  • Humans
  • Male
  • Nursing Homes*
  • Off-Label Use
  • Rationalization*

Substances

  • Antipsychotic Agents