A minimized designer protein for facile biofabrication of ZnS:Mn immuno-quantum dots

Chem Commun (Camb). 2015 Feb 28;51(17):3515-7. doi: 10.1039/c4cc09531f.

Abstract

A minimized protein consisting of a linear ZnS-binding peptide fused to an antibody-binding domain supports the one-step aqueous synthesis of Mn-doped ZnS nanocrystals that exhibit smaller size, brighter fluorescence and improved antibody-binding relative to those made with the original designer protein.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Antibodies / immunology*
  • Fluorescence
  • Manganese / chemistry*
  • Nanoparticles / chemistry
  • Particle Size
  • Quantum Dots*
  • Staphylococcal Protein A / chemistry*
  • Staphylococcus aureus / chemistry
  • Sulfides / chemistry*
  • Surface Properties
  • Zinc Compounds / chemistry*

Substances

  • Antibodies
  • Staphylococcal Protein A
  • Sulfides
  • Zinc Compounds
  • Manganese
  • zinc sulfide