The Role of Acoustic Radiation Force Impulse Elastography in the Differentiation of Infectious and Neoplastic Liver Lesions

Ultrason Imaging. 2015 Oct;37(4):312-22. doi: 10.1177/0161734614566697. Epub 2015 Jan 7.

Abstract

We aimed to evaluate the effectiveness of acoustic radiation force impulse (ARFI) elastography in differentiating between hepatic lesions. The prospective study included 117 patients with liver masses. Shear wave velocity (SWV) values for lesions were determined by ARFI imaging and compared statistically. The difference between SWV values for benign and malignant hepatic masses was significant (p < 0.01). The threshold SWV value for malignant hepatic lesions was established at 2.52 m/s, and the sensitivity and specificity of this cut-off value were 97% and 66%, respectively. We concluded that ARFI elastography provides supplementary data that aid in the differential diagnosis of liver masses.

Keywords: acoustic radiation force impulse (ARFI); focal liver lesions; ultrasound.

MeSH terms

  • Adult
  • Aged
  • Diagnosis, Differential
  • Elasticity Imaging Techniques*
  • Female
  • Humans
  • Liver / diagnostic imaging
  • Liver Diseases / diagnostic imaging
  • Liver Neoplasms / diagnostic imaging*
  • Male
  • Middle Aged
  • Prospective Studies
  • ROC Curve
  • Reproducibility of Results
  • Sensitivity and Specificity