Tanycytic ependymoma in a 76-year-old Puerto Rican male

Int J Clin Exp Pathol. 2014 Oct 15;7(11):7789-94. eCollection 2014.

Abstract

Ependymoma is a slowly growing tumor in children and young adults originating from the wall of the ventricles or from the spinal canal that is composed of neoplastic ependymal cells. Tanycytic ependymoma is a rare variant of ependymoma usually arising in the intra medullary spine. The World Health Organization classifies the tanycytic ependymoma as a grade II tumor. The diagnosis of tanycytic ependymoma is challenging since the morphology of the lesions resemble those found in schwannoma and astrocytomas. In the present study, we show a case of a 76 years old male with a progressive paraparesis for 8 years, due to a spinal tumor. Radiological and histological studies were used to classify the tumor as tanycytic ependymoma. Therefore, it is important to be aware of tanycytic ependymoma and its immunohistochemistry profile in older patients, especially within the Caribbean Hispanic population. To our knowledge this is the oldest patient known to have this rare tumor and the first case reported in Puerto Rico.

Keywords: Caribbean Hispanic; Tanycytic ependymoma; ethnicity; spinal cord; tumor.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Ependymoglial Cells / pathology*
  • Ependymoma / pathology*
  • Ependymoma / surgery
  • Humans
  • Laminectomy
  • Lumbar Vertebrae
  • Magnetic Resonance Imaging
  • Male
  • Puerto Rico
  • Spinal Cord Neoplasms / pathology*
  • Spinal Cord Neoplasms / surgery
  • Thoracic Vertebrae
  • Treatment Outcome