Draft Genome Sequence of Bivalent Clostridium botulinum Strain IBCA10-7060, Encoding Botulinum Neurotoxin B and a New FA Mosaic Type

Narjol Gonzalez-Escalona; Nagarajan Thirunavukkarasu; Ajay Singh; Magaly Toro; Eric W Brown; Donald Zink; Andreas Rummel; Shashi K Sharma

doi:10.1128/genomeA.01275-14

Draft Genome Sequence of Bivalent Clostridium botulinum Strain IBCA10-7060, Encoding Botulinum Neurotoxin B and a New FA Mosaic Type

Genome Announc. 2014 Dec 11;2(6):e01275-14. doi: 10.1128/genomeA.01275-14.

Authors

Narjol Gonzalez-Escalona¹, Nagarajan Thirunavukkarasu¹, Ajay Singh¹, Magaly Toro¹, Eric W Brown¹, Donald Zink², Andreas Rummel³, Shashi K Sharma⁴

Affiliations

¹ Division of Microbiology, Office of Regulatory Science, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland, USA.
² Office of the Center Director, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland, USA.
³ Institut für Toxikologie, Medizinische Hochschule Hannover, Niedersachsen, Germany.
⁴ Division of Microbiology, Office of Regulatory Science, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland, USA shashi.sharma@fda.hhs.gov.

Abstract

Here we report the genome sequence of a Clostridium botulinum strain IBCA10-7060 producing botulinum neurotoxin serotype B and a new toxin serotype. Multilocus sequence typing analysis revealed that this strain belongs to a new sequence type, and whole-genome single nucleotide polymorphism analysis showed that this strain clustered with strains in lineage 2 from group I.