Nerve growth factor receptor immunoreactivity in the neuronal perikarya of human sensory and sympathetic nerve ganglia

Neurology. 1989 Jul;39(7):937-41. doi: 10.1212/wnl.39.7.937.

Abstract

We examined immunohistochemically the dorsal root ganglia, sympathetic ganglia, spinal cord, ventral and dorsal roots, and sciatic nerves obtained at autopsy from adult humans, using a monoclonal antibody against the human nerve growth factor receptor. We observed labelling in a granular pattern in the neuronal perikarya of dorsal root and sympathetic nerve ganglia. Ventral horn cells and axons were not labelled.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antibodies, Monoclonal
  • Ganglia, Spinal / analysis*
  • Ganglia, Spinal / cytology
  • Ganglia, Sympathetic / analysis*
  • Ganglia, Sympathetic / cytology
  • Humans
  • Immunohistochemistry
  • Neurons / analysis
  • Receptors, Cell Surface / analysis*
  • Receptors, Nerve Growth Factor

Substances

  • Antibodies, Monoclonal
  • Receptors, Cell Surface
  • Receptors, Nerve Growth Factor