Catheter-related bacteremia by Cupriavidus metallidurans

Diagn Microbiol Infect Dis. 2015 Jan;81(1):9-12. doi: 10.1016/j.diagmicrobio.2014.09.015. Epub 2014 Sep 28.

Abstract

Cupriavidus bacteremia is a rare infection and identification of the pathogen is difficult. We present four cases of bacteremia by Cupriavidus metallidurans that were initially identified to the genus level by both Bruker and Vitek matrix-assisted laser desorption ionization-time of flight mass spectrometry and later identified to the species level by 16S rRNA gene sequencing. To our knowledge, these are the first cases of C. metallidurans catheter-related infections. Patients were successfully treated with antibiotic therapy and catheter removal.

Keywords: Catheter-related bacteremia; Cupriavidus.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Bacteremia / drug therapy
  • Bacteremia / etiology
  • Bacteremia / microbiology*
  • Catheter-Related Infections / drug therapy
  • Catheter-Related Infections / etiology
  • Catheter-Related Infections / microbiology*
  • Cupriavidus / genetics*
  • Cupriavidus / isolation & purification
  • Cupriavidus / pathogenicity*
  • Female
  • Gram-Negative Bacterial Infections / drug therapy
  • Gram-Negative Bacterial Infections / etiology
  • Gram-Negative Bacterial Infections / microbiology*
  • Humans
  • Male
  • Middle Aged
  • Penicillanic Acid / analogs & derivatives
  • Penicillanic Acid / therapeutic use
  • Piperacillin / therapeutic use
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
  • Tazobactam

Substances

  • Penicillanic Acid
  • Tazobactam
  • Piperacillin