Osteoradionecrosis of the mandible: through a radiologist's eyes

Clin Radiol. 2015 Feb;70(2):197-205. doi: 10.1016/j.crad.2014.09.012. Epub 2014 Oct 18.

Abstract

Head and neck malignancies constitute a major cause of morbidity and mortality all over the world. Radiotherapy plays a pivotal role in the management of these tumours; however, it has associated complications, with mandibular osteoradionecrosis (ORN) being one of the gravest orofacial complications. Early diagnosis, extent evaluation, and detection of complications of ORN are imperative for instituting an appropriate management protocol. ORN can closely mimic tumour recurrence, the differentiation of which has obvious clinical implications. The purpose of the present review is to acquaint the radiologist with the imaging features of mandibular ORN and the ways to differentiate ORN from tumour recurrence.

Publication types

  • Review

MeSH terms

  • Fluorodeoxyglucose F18
  • Humans
  • Magnetic Resonance Imaging / methods
  • Mandible / diagnostic imaging
  • Mandible / pathology
  • Mandibular Diseases / diagnosis*
  • Mandibular Diseases / pathology
  • Mandibular Diseases / therapy
  • Osteoradionecrosis / diagnosis*
  • Osteoradionecrosis / pathology
  • Osteoradionecrosis / therapy
  • Positron-Emission Tomography / methods
  • Radiopharmaceuticals
  • Tomography, Emission-Computed, Single-Photon / methods
  • Tomography, X-Ray Computed / methods

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18