Muscle velocity and inertial force from phase contrast MRI

J Magn Reson Imaging. 2015 Aug;42(2):526-32. doi: 10.1002/jmri.24807. Epub 2014 Nov 25.

Abstract

Purpose: To evaluate velocity waveforms in muscle and to create a tool and algorithm for computing and analyzing muscle inertial forces derived from 2D phase contrast (PC) magnetic resonance imaging (MRI).

Materials and methods: PC MRI was performed in the forearm of four healthy volunteers during 1 Hz cycles of wrist flexion-extension as well as in the lower leg of six healthy volunteers during 1 Hz cycles of plantarflexion-dorsiflexion. Inertial forces (F) were derived via the equation F = ma. The mass, m, was derived by multiplying voxel volume by voxel-by-voxel estimates of density via fat-water separation techniques. Acceleration, a, was obtained via the derivative of the PC MRI velocity waveform.

Results: Mean velocities in the flexors of the forearm and lower leg were 1.94 ± 0.97 cm/s and 5.57 ± 2.72 cm/s, respectively, as averaged across all subjects; the inertial forces in the flexors of the forearm and lower leg were 1.9 × 10(-3) ± 1.3 × 10(-3) N and 1.1 × 10(-2) ± 6.1 × 10(-3) N, respectively, as averaged across all subjects.

Conclusion: PC MRI provided a promising means of computing muscle velocities and inertial forces-providing the first method for quantifying inertial forces.

Keywords: PC MRI; biomechanical models; force; muscle motion; muscle velocity; velocimetry.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acceleration
  • Adult
  • Female
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods
  • Imaging, Three-Dimensional / methods
  • Magnetic Resonance Imaging / methods*
  • Male
  • Movement / physiology*
  • Muscle Contraction / physiology*
  • Muscle, Skeletal / anatomy & histology*
  • Muscle, Skeletal / physiology*
  • Pattern Recognition, Automated / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Stress, Mechanical
  • Wrist Joint / physiology