Abstract
Here, we report a case of a Bulgarian patient with imported falciparum malaria that manifested 6 days after his arrival in Bulgaria, which was complicated by bloody diarrhea 2 days later. Blood smear revealed high parasitemia, with annular forms and gametocytes of Plasmodium falciparum. In addition, RNA of the Crimean-Congo hemorrhagic fever (CCHF) virus was detected in the blood sample by real-time reverse transcription (RT)-PCR and nested RT-PCR. The obtained sequence was found to be clustered within the Europe 1 lineage close to the other Bulgarian strains. Notably, the two infectious diseases may appear with many similar symptoms that are difficult to distinguish.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Blood / parasitology
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Blood / virology
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Bulgaria
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Coinfection / parasitology
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Coinfection / pathology*
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Coinfection / virology
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Fatal Outcome
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Hemorrhagic Fever Virus, Crimean-Congo / isolation & purification
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Hemorrhagic Fever, Crimean / complications*
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Hemorrhagic Fever, Crimean / pathology
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Hemorrhagic Fever, Crimean / virology
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Humans
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Malaria, Falciparum / complications*
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Malaria, Falciparum / parasitology
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Malaria, Falciparum / pathology
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Male
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Microscopy
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Molecular Sequence Data
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Plasmodium falciparum / isolation & purification
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RNA, Viral / blood
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Reverse Transcriptase Polymerase Chain Reaction
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Sequence Analysis, DNA