Abstract
Sequencing of serial isolates of extensively drug-resistant tuberculosis highlights how drug resistance develops within a single patient and reveals unexpected levels of pathogen diversity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Evolution, Molecular*
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Extensively Drug-Resistant Tuberculosis / genetics*
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Extensively Drug-Resistant Tuberculosis / microbiology
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Genetic Variation
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Genotype
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Humans
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Microbial Sensitivity Tests
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Mycobacterium tuberculosis / genetics*
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Mycobacterium tuberculosis / pathogenicity
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Polymorphism, Single Nucleotide