Specificity and sensibility of 9-Itens Wearing-off Questionnaire in Brazilian Parkinson disease patient sample

Arq Neuropsiquiatr. 2014 Nov;72(11):867-73. doi: 10.1590/0004-282x20140166.

Abstract

Objective: (1) To evaluate whether the Nine Items Questionnaire (WOQ-9) for the detection of wearing-off (WO) in Parkinson Disease (PD), by means of its screening ability, is a helpful tool to assist neurologists in diagnosing WO; (2) To determine the sensitivity and the specificity of a free Brazilian Portuguese translation of WOQ-9.

Method: A sample obtained by convenience included 60 patients. The WOQ-9 was answered by the patients themselves before their routine consultations. The detection of the WO by the WOQ-9 was compared with the neurologist assessment. Statistical significance was 5%.

Results: The WOQ-9 showed sensitivity of 100%, specificity of 10.3%, positive and negative predictive values of 54.4% and 100% respectively. The identification of WO by the WOQ-9 was congruent in 54.5% of cases with neurological evaluation.

Conclusion: The WOQ-9 is a convenient screening tool to aid physicians to detect WO in PD patients, and it is a quick and easy self-administered questionnaire.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Brazil
  • Cross-Sectional Studies
  • Dopamine Agents / therapeutic use
  • Female
  • Humans
  • Levodopa / therapeutic use
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Parkinson Disease / diagnosis*
  • Parkinson Disease / drug therapy
  • Reference Values
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Statistics, Nonparametric
  • Surveys and Questionnaires / standards*
  • Translations

Substances

  • Dopamine Agents
  • Levodopa