Adolescent vaccine co-administration and coverage in New York City: 2007-2013

Pediatrics. 2014 Dec;134(6):e1576-83. doi: 10.1542/peds.2014-1452. Epub 2014 Nov 10.

Abstract

Objectives: To investigate adolescent vaccination in New York City, we assessed tetanus, diphtheria, and acellular pertussis (Tdap), meningococcal conjugate (MCV4), and human papillomavirus (HPV) vaccine uptake, vaccine co-administration, and catch-up coverage over time.

Methods: We analyzed data from the Citywide Immunization Registry, a population-based immunization information system, to measure vaccine uptake and co-administration, defined as a Tdap vaccination visit where MCV4 or HPV vaccine was co-administered, among 11-year-olds. Catch-up vaccinations were evaluated through 2013 for adolescents born 1996 to 2000, by birth cohort. HPV vaccination among boys included data from 2010 to 2013.

Results: Adolescent vaccine administration was greatest during the back-to-school months of August to October and was highest for Tdap. Although MCV4 uptake improved over the study years, HPV vaccine uptake among girls stagnated; boys achieved similar uptake of HPV vaccine by 2012. By 2013, 65.4% had MCV4 co-administered with Tdap vaccine, whereas 28.4% of girls and 25.9% of boys had their first dose of HPV vaccine co-administered. By age 17, Tdap and MCV4 vaccination coverage increased to 97.5% and 92.8%, respectively, whereas ≥1-dose and 3-dose HPV vaccination coverage were, respectively, 77.5% and 53.1% for girls and 49.3% and 21.6% for boys. Age-specific vaccination coverage increased with each successive birth cohort (P < .001).

Conclusions: From 2007 to 2013, there were greater improvements in Tdap and MCV4 vaccination than HPV vaccination, for which co-administration with Tdap vaccine and coverage through adolescence remained lower. Parent and provider outreach efforts should promote timely HPV vaccination for all adolescents and vaccine co-administration.

Keywords: HPV vaccine; MCV4; Tdap; adolescent immunization; co-administration.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Cohort Studies
  • Diphtheria-Tetanus-Pertussis Vaccine / administration & dosage
  • Female
  • Humans
  • Immunization, Secondary / trends
  • Male
  • Mass Vaccination / trends*
  • Meningococcal Vaccines / administration & dosage
  • New York City
  • Papillomavirus Vaccines / administration & dosage
  • Urban Population*
  • Vaccines, Combined / administration & dosage*

Substances

  • Diphtheria-Tetanus-Pertussis Vaccine
  • Meningococcal Vaccines
  • Papillomavirus Vaccines
  • Vaccines, Combined
  • serogroup C meningococcal conjugate vaccine