A Case of AML-M2 with Sole Interstitial Deletion in 9q Without AML1-ETO/Inv 16 Rearrangement and FLT3/NPMI Mutations

G Sandhya Devi; Faiq Ahmed; Manasi C Mundada; S Sudha Murthy; Krishna Mohan Mallavarapu

doi:10.1007/s12288-013-0322-8

A Case of AML-M2 with Sole Interstitial Deletion in 9q Without AML1-ETO/Inv 16 Rearrangement and FLT3/NPMI Mutations

Indian J Hematol Blood Transfus. 2014 Sep;30(Suppl 1):186-9. doi: 10.1007/s12288-013-0322-8. Epub 2014 Jan 23.

Authors

G Sandhya Devi¹, Faiq Ahmed¹, Manasi C Mundada¹, S Sudha Murthy¹, Krishna Mohan Mallavarapu²

Affiliations

¹ Department of Laboratory Medicine, Basavatarakam Indo American Cancer Hospital and Research Institute, Rd No 14 Banjara Hills, Hyderabad, 500034 India.
² Department of Medical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, 500034 India.

Abstract

Conventional/molecular cytogenetics is important in identification of genomic abnormalities, for prognostication and in risk stratification of de novo patients with acute myeloid leukemias (AML). Here we present an AML M2 case showing the sole karyotypic abnormality, the rare interstitial deletion in the long arm of chromosome 9 with the loss of segment q12-q13.

Keywords: AML-M2; CD7; Conventional cytogenetics; Del 9q.

Publication types

Case Reports